Journal
BIOCONJUGATE CHEMISTRY
Volume 20, Issue 1, Pages 5-14Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bc800278e
Keywords
-
Categories
Funding
- Ministry of Health and Welfare
- Ministry of Education, and Science and Technology, Republic of Korea
Ask authors/readers for more resources
Small interfering RNA (siRNA) has been chemically conjugated to a variety of bioactive molecules, lipids, polymers, peptides, and inorganic nanostructured materials to enhance their pharmacokinetic behavior, cellular uptake, target specificity, and safety. To efficiently deliver siRNAs to the target cells and tissues, many different siRNA bioconjugates were synthesized and characterized, and their gene silencing efficiencies were tested in vitro and in vivo. In this review, recent developments of siRNA bioconjugates are summarized.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
