Journal
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
Volume 200, Issue 1-3, Pages 57-69Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S1387-3806(00)00302-X
Keywords
molecular recognition; host-guest chemistry; electrospray ionization; complexation
Ask authors/readers for more resources
The use of mass spectrometry for the study of host-guest complexation and molecular recognition involving either synthetic hosts or biological hosts has been a growing area of research over the past decade. Mass spectrometry has allowed the first studies of host-guest chemistry in a solvent-free environment in which both size selectivity and electronic effects influence the formation, reactions and stabilities of gas-phase host-guest complexes. Aspects of solution equilibria, such as the determination of binding selectivities of hosts and binding constants, may be examined by using electrospray ionization to transfer noncovalent complexes from solution to the gas phase for analysis. This article will review some of the highlights involving the application of mass spectrometry for solving problems in the area of molecular recognition. (C) 2000 Elsevier Science B.V.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available