4.4 Article

Passive micromixer using by convection and surface tension effects with air-liquid interface

Journal

BIOCHIP JOURNAL
Volume 7, Issue 4, Pages 361-366

Publisher

KOREAN BIOCHIP SOCIETY-KBCS
DOI: 10.1007/s13206-013-7407-1

Keywords

Passive micromixer; Surface tension; Convection; Marangoni effect; Autonomous operation

Funding

  1. National Research Foundation of Korea (NRF)
  2. Korean government (MEST) [2013046403]
  3. United States National Library of Medicine [5T15 LM007359]

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This article describes a passive micromixer that utilizes an air-liquid interface and surface tension effects to enhance fluid mixing via convection and Marangoni effects. Performance of the microfluidic component is tested within a passive-pumping-based device that consists of three microchannels connected in succession using passive micro-mixers. Mixing was quantified at 5 key points along the length of the device using microscope images of patterned streams of Alexa 488 fluorescent-dyed water and pure DI water flowing through the device. The passive micro-mixer mixed fluid 15-20 times more effectively than diffusion between laminar flow streams alone and is a novel micro-mixer embodiment that provides an additional strategy for removing external components from microscale devices for simpler, autonomous operation.

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