4.6 Review

High-performance liquid chromatography chiral stationary phases based on low-molecular-mass selectors

Journal

JOURNAL OF CHROMATOGRAPHY A
Volume 906, Issue 1-2, Pages 35-50

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/S0021-9673(00)00953-5

Keywords

reviews; chiral stationary phases, LC; enantiomer separation; brush-type chiral stationary phases; receptor-like chiral stationary phases; dynamic enantioselective chromatography; chiral selectors

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A review of HPLC chiral stationary phases (CSPs) based on low molecular mass selectors is given. The review is focused on brush- and monomeric-type CSPs obtained by covalent linkage of chiral selectors, with emphasis on those obtained by total synthesis. Emphasis is given to new, emerging aspects like enantioseparations on receptor-like chiral stationary phases and dynamic enantioselective chromatography of stereolabile compounds. (C) 2001 Elsevier Science B.V. All rights reserved.

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