Journal
LANCET
Volume 357, Issue 9251, Pages 195-196Publisher
LANCET LTD
DOI: 10.1016/S0140-6736(00)03594-7
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The UK was the first country to use meningococcal serogroup C conjugate (MCC) vaccines, which were licensed on the basis of Immunogenicity and safety data but without a formal efficacy study. Increased surveillance during the first 9 months since introduction has shown that short-term efficacy of the MCC vaccine in England was 97% (95% CI 77-99) for teenagers and 92% (65-98) for toddlers. These early results confirm the superiority of MCC over plain C polysaccharide vaccines, which are ineffective in young children.
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