4.8 Article

Meiotic recombination: Making and breaking go hand in hand

Journal

CURRENT BIOLOGY
Volume 11, Issue 2, Pages R45-R48

Publisher

CELL PRESS
DOI: 10.1016/S0960-9822(01)00013-6

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Accurate segregation of homologous chromosomes at the first meiotic division requires the tight coordination of DNA replication, homologous recombination and chromosome organization. Recent studies suggest that the initiation of meiotic recombination is mechanistically coupled to premeiotic DNA replication.

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