Journal
BIOCHIMIE
Volume 93, Issue 1, Pages 39-45Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biochi.2010.04.016
Keywords
Nutrition; Obesity; Lipid; Inflammation; Endotoxemia
Categories
Funding
- Institut Benjamin Delessert
- Societe Francaise de Nutrition
- INRA & CNIEL Marie-Caroline
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Metabolic diseases such as obesity are characterized by a subclinical inflammatory state that contributes to the development of insulin resistance and atherosclerosis. Recent reports also indicate that (i) there are alterations of the intestinal microbiota in metabolic diseases and (ii) absorption of endogenous endotoxins (namely lipopolysaccharides, LPS) can occur, particularly during the digestion of lipids. The aim of the present review is to highlight recently gained knowledge regarding the links between high fat diets, lipid digestion, intestinal microbiota and metabolic endotoxemia & inflammation. (C) 2010 Elsevier Masson SAS. All rights reserved.
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