Journal
TRENDS IN CELL BIOLOGY
Volume 11, Issue 2, Pages 49-54Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0962-8924(00)01880-8
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- Wellcome Trust [073915] Funding Source: Medline
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Chromosomal passengers are proteins that move from centromeres to the spindle midzone during mitosis. Recent experiments show that the passengers inner centromere protein (INCENP) and aurora-B kinase are in a macromolecular complex that might also contain a third passenger, survivin. The chromosomal passenger complex functions throughout mitosis in chromosome condensation and segregation, and at the end of mitosis, in the completion of cytokinesis.
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