Journal
CURRENT OPINION IN NEUROBIOLOGY
Volume 11, Issue 1, Pages 118-126Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-4388(00)00182-3
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In vivo studies indicate that synaptic activity promotes dendritic arbor elaboration at early stages of brain development. At later stages of development, synaptic activity stabilizes dendritic structure. The different roles of synaptic activity with respect to structural plasticity probably reflect the regulated spatiotemporal expression of key components within signaling pathways.
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