Journal
ANALYST
Volume 140, Issue 17, Pages 5849-5854Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5an00918a
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Funding
- National Natural Science Foundation of China [21222502, 91213305]
- Ministry of Science and Technology [2011CB933201]
- Youth Innovation Promotion Association (CAS)
- CAS/SAFEA International Partnership Program for Creative Research Teams
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDA09030305]
- National High Technology Research and Development Program of China [2012AA022703]
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Here, we explore the new application of an old molecule. We find that the tetraphenylethene-indolium molecule (TPE-indo) can both image the mitochondria (in the aggregated state), and indicate mitochondrial activity by the fluorescence change of TPE-indo. TPE-indo shows good photostability, longer emission wavelength, targeting effect for mitochondria, and better response to the changes of the mitochondrial membrane potential (Delta Psi(m)).
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