Journal
PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 20, Issue 2, Pages 197-206Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00006454-200102000-00017
Keywords
candidiasis; cell-mediated immunity; immunodeficiency; cytokine production; immunotherapy; transfer factors
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Chronic mucocutaneous candidiasis should be viewed as a spectrum of disorders in which the patients have persistent and/or recurrent candidiasis of the skin, nails and mucous membranes. Some of the conditions have genetic predispositions, A common immunologic abnormality is failure of the patient's T lymphocytes to produce cytokines that are essential for expression of cell-mediated immunity to Candida, Antifungal drugs are effective in clearing the infections, and treatments that restore cellular immunity have produced long term remissions.
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