Journal
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Volume 1793, Issue 1, Pages 20-26Publisher
ELSEVIER
DOI: 10.1016/j.bbamcr.2008.07.005
Keywords
Membrane dynamic; Mitochondrial fusion; Dynamin
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Funding
- NIH [1 R01 EY015924]
- NATIONAL EYE INSTITUTE [R01EY015924] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM062942] Funding Source: NIH RePORTER
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This review is focused on mitochondrial membrane fusion, which is a highly conserved process from yeast to human cells. We present observations from both yeast and mammalian cells that have provided insights into the mechanism of mitochondrial fusion and speculate on how the key players, which are dynamin-related GTPases do the work of membrane tethering and fusion. (C) 2008 Published by Elsevier B.V.
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