4.4 Article

Direct transformation of aldehydes to nitriles using iodine in ammonia water

Journal

TETRAHEDRON LETTERS
Volume 42, Issue 6, Pages 1103-1105

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(00)02195-X

Keywords

aldehydes; nitriles; solvents and solvent effects

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Treatment of aromatic, heterocyclic, aliphatic, conjugated, and polyhydroxy aldehydes with iodine in ammonia water at room temperature for a short period gave the corresponding nitriles in high yields. (C) 2001 Elsevier Science Ltd. All rights reserved.

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