4.8 Article

Near-field scanner for moving molecules

Journal

PHYSICAL REVIEW LETTERS
Volume 86, Issue 7, Pages 1378-1381

Publisher

AMERICAN PHYSICAL SOC
DOI: 10.1103/PhysRevLett.86.1378

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Funding

  1. PHS HHS [NIH O1506] Funding Source: Medline

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We have fabricated using electron beam nanolithography a fixed slit near-held optical scanning device which uses near-field fluorimetry to achieve 200 nm spatial resolution of objects moving over the slits. We explore the basic physics of operating narrow slits in the waveguide cutoff mode and present data from the passage of extended double-stranded DNA molecules passing over the slits as a first example of how this device can be used to do ultrahigh spatial resolution mapping of long polymers.

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