Journal
NEUROLOGY
Volume 56, Issue 3, Pages 415-418Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/WNL.56.3.415
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Funding
- NCRR NIH HHS [MO1 RR00645, MO1 RR00722, MO1 RR00044] Funding Source: Medline
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Cognitive and functional outcomes are of primary interest in the design of efficacy trials in HIV-associated cognitive impairment. In a longitudinal cohort study, weak associations were found between measures of cognitive performance and commonly used measures of daily functioning (mostly self-report measures) in HIV-infected individuals. Modifications of current functional scales or new functional instruments are needed to assess the clinical relevance of cognitive changes in clinical trials of HIV-associated cognitive impairment.
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