Journal
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
Volume 1841, Issue 3, Pages 314-318Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbalip.2013.09.011
Keywords
Acylceramide; Corneocyte lipid envelope; Essential fatty acid deficiency; Gaucher's disease; Neutral lipid storage disease; Refsum disease
Funding
- NIH grant [AR019098]
- Rene Touraine Foundation
- Medical Research Service, Department of Veterans Affairs
Ask authors/readers for more resources
Corneocytes in mammalian stratum corneum are surrounded by a monolayer of covalently bound omega-OH-ceramides that form the corneocyte (-bound) lipid envelope (CLE). We review here the structure, composition, and possible functions of this structure, with insights provided by inherited and acquired disorders of lipid metabolism. This article is part of a Special Issue entitled The Important Role of Lipids in the Epidermis and their Role in the Formation and Maintenance of the Cutaneous Barrier. Guest Editors: Kenneth R. Feingold and Peter Elias. (C) 2013 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
