Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 909, Issue 2, Pages 225-236Publisher
ELSEVIER
DOI: 10.1016/S0021-9673(00)01099-2
Keywords
stationary phases; LC; mobile phase composition; microcystins; toxins; nodularin
Ask authors/readers for more resources
Four C-18 columns and a novel amide C-16 column were assessed in the HPLC separation of eight microcystins and nodularin-R. Gradient mobile phases of acetonitrile combined with trifluoroacetic acid, formic acid or ammonium acetate were compared. Special attention was paid to the resolution of four possible coeluting microcystin pairs. Generally speaking, the acidic mobile phases were superior to the ammonium acetate-based mobile phase in terms of resolution and selectivity. The amide C-16 column had the best overall performance and unique selectivity properties. (C) 2001 Elsevier Science B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available