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The life of lipid droplets

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbalip.2008.10.009

Keywords

Adiposome; Triglyceride; Steryl ester; Fat storage; Organelle dynamic

Funding

  1. NIH [R21-DK78254]
  2. International Human Frontier Science Program Organization
  3. J. David Gladstone Institutes
  4. Max Planck Society
  5. NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R21DK078254] Funding Source: NIH RePORTER

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Lipid droplets are the least characterized of cellular organelles. Long considered simple lipid storage depots, these dynamic and remarkable organelles have recently been implicated in many biological processes, and we are only now beginning to gain insights into their fascinating lives in cells. Here we examine what we know of the life of lipid droplets. We review emerging data concerning their cellular biology and present our thoughts on some of the most salient questions for investigation. (C) 2008 Elsevier B.V. All rights reserved.

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