Journal
JOURNAL OF MAGNETIC RESONANCE IMAGING
Volume 13, Issue 3, Pages 417-420Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/jmri.1060
Keywords
MRI; murine blastocyst; in-vitro development; safety; embryogenesis
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Although no ionizing radiation Is Involved, patients undergoing magnetic resonance imaging (MRI) are exposed to powerful static magnetic fields, magnetic field gradients, and radio-frequency fields that may be potentially damaging. Our study aims to document the effect of AM imaging sequences on early murine embryo development (two-cell to blastocyst stage) in vitro. Two-cell murine embryos were exposed to various lengths of MRI using pulse sequences employed in present day clinical Imaging. Early murine embryo development was documented in vitro, and blastocyst development rates were computed for both the control and exposed groups. There were no significant differences detected in the rate of blastocyst formation between the control groups and the embryos exposed to MRI. (C) 2001 Wiley-Liss, Inc.
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