Journal
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
Volume 11, Issue 1, Pages 40-52Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jbn.2015.1962
Keywords
Nanocomposite Hydrogel; Drug Delivery; Tissue Engineering
Funding
- National Natural Science Foundation of China [20904042, 21004080]
- Natural Science Foundation of Jiangshu Provinice, China [BK20131187]
- Program for New Century Excellent Talents in University of the Ministry of Education of China [NCET-09-0818]
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Traditional hydrogels usually possess inferior mechanical properties as well as lacking multi-functionalities. Nano-sized particles/fillers, both inorganic and organic materials, have unique chemical, physical, and biological functions, and have been extensively studied as biomaterials or bio-functional materials. Nanocomposite hydrogels, which combine the advantages of both nano-fillers and hydrogel matrices, may result in improved mechanical and biological properties and find their potential applications in biomedical field. This paper reviews recent developments in the synthesis, preparation, and characterization of nanocomposite hydrogels; their biomedical applications, such as drug delivery matrices and tissue engineering scaffolding materials are also summarized.
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