Journal
TRENDS IN IMMUNOLOGY
Volume 22, Issue 3, Pages 160-168Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1471-4906(01)01865-8
Keywords
-
Categories
Ask authors/readers for more resources
Tuberculosis (TB) is the biggest killer worldwide of any infectious disease, a situation worsened by the advent of the HIV epidemic and the emergence of multi-drug resistant strains of Mycobacterium tuberculosis. The existing vaccine, Mycobacterium bovis bacille Calmette-Guerin (BCG). has proven inefficient in several recent field trials. There is currently intense research using cutting-edge vaccine technology to combat this ancient disease, However, it is necessary to understand why BCG has failed before we can rationally develop the next generation of vaccines. Several hypotheses that might explain the failure of BCG and the strategies designed to address these shortcomings are discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available