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Glycobiology in the cytosol: The bitter side of a sweet world

Journal

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Volume 1790, Issue 2, Pages 81-94

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbagen.2008.09.009

Keywords

Cytosol; Glycosylation; Lectin; Glycosidase; Glycosyltransferase; Glycobiology

Funding

  1. Ministry of Education, Culture, Sports, Science and Technology of Japan.

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Progress in glycobiology has undergone explosive growth over the past decade with more of the researchers now realizing the importance of glycan chains ill Various inter- and intracellular processes. However, there is still an area of glycobiology awaiting exploration. This is especially the case for the field of glycobiology ill the cytosol which remains rather poorly understood. Yet evidence is accumulating to demonstrate that the glycoconjugates and their recognition molecules (i.e. lectins) are often present in this subcellular compartment. (C) 2008 Elsevier B.V. All rights reserved.

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