Journal
FRONTIERS IN BIOSCIENCE-LANDMARK
Volume 6, Issue -, Pages D388-D405Publisher
FRONTIERS IN BIOSCIENCE INC
DOI: 10.2741/Goldberg
Keywords
triglyceride; chylomicrons; heparin; proteoglycans; hyperlpidemai; review
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Lipoprotein lipase (LpL) is the primary enzyme responsible for conversion of lipoprotein triglyceride into free fatty acids and monoglyderides. This permits their uptake into muscle and adipose. The roles of this enzyme in normal and altered physiology are reviewed. In addition, the relationship of LpL activity and genetic variations of LpL and human disease are summarized.Lipoprotein lipase (LpL) is the primary enzyme responsible for conversion of lipoprotein triglyceride into free fatty acids and monoglyderides. This permits their uptake into muscle and adipose. The roles of this enzyme in normal and altered physiology are reviewed. In addition, the relationship of LpL activity and genetic variations of LpL and human disease are summarized.
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