Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 45, Issue 3, Pages 901-904Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.45.3.901-904.2001
Keywords
-
Categories
Ask authors/readers for more resources
Enterocin P is a bacteriocin produced by Enterococcus faecium P13, We studied the mechanism of its bactericidal action using enterocin-P-sensitive E, faecium T136 cells. The bacteriocin is incapable of dissipating the transmembrane pH gradient. On the other hand, depending on the buffer used, enterocin P dissipates the transmembrane potential. Enterocin P efficiently elicits efflux of potassium ions, but not of intracellularly accumulated anions like phosphate and glutamate, Taken together, these data demonstrate that enterocin P forms specific, potassium ion-conducting pores in the cytoplasmic membrane of target cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available