4.2 Article

Effect of morphine on the number and branching of astrocytes in various regions of rat brain

Journal

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 131, Issue 3, Pages 248-250

Publisher

SPRINGER
DOI: 10.1023/A:1017699315355

Keywords

rat; brain; astrocytes; morphine; immunocytochemistry

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We studied the effects of morphine in high doses on astrocytes in the nucleus accumbens, lateral septum, and caudate nucleus of rat brain. Activation of astrocytes in the nucleus accumbens and lateral septal nucleus was manifested in hyperplasia and elongation of astrocyte processes. In the caudate nucleus, the total length of astrocyte processes and branching of individual astrocytes decreased.

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