Journal
ANALYST
Volume 140, Issue 5, Pages 1421-1427Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4an02169j
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Funding
- Defense Threat Reduction Agency-Joint Science and Technology Office for Chemical and Biological Defense [HDTRA1-13-1-0002]
- China Scholarship Council
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Towards addressing the need for detecting and eliminating bio-threats, we describe a micromotor-based approach for screening, capturing, isolating and destroying anthrax simulant spores in a simple and rapid manner with minimal sample processing. The B. globilli antibody-functionalized micromotors can recognize, capture and transport B. globigii spores in environmental matrices, while showing non-interactions with excess of non-target bacteria. Efficient destruction of the anthrax simulant spores is demonstrated via the micromotor-induced mixing of a mild oxidizing solution. The new micromotor-based approach paves a way to dynamic multifunctional systems that rapidly recognize, isolate, capture and destroy biological threats.
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