Journal
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Volume 1818, Issue 4, Pages 1085-1090Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbamem.2011.08.027
Keywords
Mitochondrial import; Membrane protein; Mitochondrial translocase; Protein insertion into mitochondrial membrane
Categories
Funding
- Deutsche Forschungsgemeinschaft [RA1048/4-1]
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Mitochondria are essential eukaryotic organelles that are surrounded by two membranes. Both membranes contain a variety of different integral membrane proteins. After three decades of research on mitochondrial biogenesis five major import complexes with more than 40 subunits altogether were identified and characterized. In the current contribution we want to draw attention to some unexplored issues regarding the integration of mitochondrial membrane proteins and to formulate crucial questions that remain unanswered. This article is part of a Special Issue entitled: Protein Folding in Membranes. (C) 2011 Elsevier B.V. All rights reserved.
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