Journal
ARCHIVES OF NEUROLOGY
Volume 58, Issue 3, Pages 365-370Publisher
AMER MEDICAL ASSOC
DOI: 10.1001/archneur.58.3.365
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Glutamate is the primary excitatory amino acid neurotransmitter in the human brain. It is important in synaptic plasticity, learning, and development. Its activity at the synaptic cleft is carefully balanced by receptor inactivation and glutamate reuptake. When this balance is upset, excess glutamate can itself become neurotoxic.
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