Journal
JOURNAL OF CRANIOFACIAL SURGERY
Volume 12, Issue 2, Pages 119-127Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001665-200103000-00005
Keywords
ameloblastoma; BMP; bioimplant; mandibular reconstruction
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A bone morphogenetic protein bioimplant was used for primary reconstruction of a 6-cm mandibular discontinuity defect, after a segmental resection of an ameloblastoma. Radiographic evidence of new bone induction was seen at 3 and 9 months, postoperatively. A biopsy was taken at 9 months demonstrated viable new bone formation at the bioimplant site. This is the first reported case using a bone morphogenetic protein bioimplant in a human, followed by histological confirmation of new bone.
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