Journal
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Volume 1798, Issue 4, Pages 750-765Publisher
ELSEVIER
DOI: 10.1016/j.bbamem.2009.07.026
Keywords
Atomic force microscopy; Biomembranes; Nanoscale organization; Real-time imaging; Supported lipid bilayers
Categories
Funding
- National Foundation for Scientific Research (FNRS)
- Universite catholique de Louvain (Fonds Speciaux de Recherche)
- Region wallonne
- Federal Office for Scientific, Technical and Cultural Affairs
- Research Department of the Communaute francaise de Belgique
- Universite de Technologie de Compiegne
- French Ministry of Research (PPF BIOMIM)
- French Region Picardie
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During the past 15 years, atomic force microscopy (AFM) has opened new opportunities for imaging supported lipid bilayers (SLBs) on the nanoscale. AFM offers a means to visualize the nanoscale structure of SLBs in physiological conditions. A unique feature of AFM is its ability to monitor dynamic events, like bilayer alteration, remodelling or digestion, upon incubation with various external agents such as drugs, detergents, proteins, peptides, nanoparticles, and solvents. Here, we survey recent progress made in the area. (C) 2009 Elsevier B.V. All rights reserved.
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