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Molecular components of the adherens junction

Journal

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Volume 1778, Issue 3, Pages 562-571

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbamem.2007.12.015

Keywords

zonula adherens; cadherin; catenin; nectin; adhesion

Funding

  1. NIGMS NIH HHS [R01 GM076561-03, R01 GM076561] Funding Source: Medline
  2. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM076561] Funding Source: NIH RePORTER

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Adherens junctions serve to couple individual cells into various arrangements required for tissue structure and function. The central structural components of adherens junctions are transmembrane adhesion receptors, and their associated actin-binding/regulatory proteins. The molecular machineries that organize these adhesion receptor complexes into higher order junction structures, and the functional consequences of this junctional organization will be discussed. Published by Elsevier B.V.

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