Journal
TRENDS IN MICROBIOLOGY
Volume 9, Issue 3, Pages 97-101Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0966-842X(01)01956-4
Keywords
-
Categories
Ask authors/readers for more resources
A range of surface proteins is anchored to the cell walls of Gram-positive pathogens such as Staphylococcus aureus by the transpeptidase sortase. Until now, sortase-like proteins and their substrates appeared to be limited mainly to such pathogens. However, by searching for sortase homologues among complete and incomplete genome sequences, we have found them to be present in almost all Gram-positives, a single Gram-negative bacterium and an archaean. There is usually more than one sortase-like protein encoded in each Gram-positive genome, and the genes encoding the sortase-like proteins are often clustered with genes encoding their likely substrates.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available