4.8 Article

GeneSplicer: a new computational method for splice site prediction

Journal

NUCLEIC ACIDS RESEARCH
Volume 29, Issue 5, Pages 1185-1190

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/29.5.1185

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Funding

  1. NLM NIH HHS [R01 LM006845, R01-LM06845] Funding Source: Medline

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GeneSplicer is a new, flexible system for detecting splice sites in the genomic DNA of various eukaryotes, The system has been tested successfully using DNA from two reference organisms: the model plant Arabidopsis thaliana and human. It was compared to six programs representing the leading splice site detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSplice, GENIO and SpliceView. In each case GeneSplicer performed comparably to the best alternative, in terms of both accuracy and computational efficiency.

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