4.8 Article

Spindles cotton on to junctions, APC and EB1

Journal

NATURE CELL BIOLOGY
Volume 3, Issue 3, Pages E67-E69

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MACMILLAN PUBLISHERS LTD
DOI: 10.1038/35060140

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Recent work in Drosophila has shown that the adherens junctions of epithelial cells provide a planar cue to orientate mitotic spindles during symmetrical division. This planar cue depends on the function of E-APC and dEB1, homologues of the adenomatous polyposis coli (APC) tumour suppressor and of the microtubule-binding yeast protein Bim1.

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