Journal
CYTOKINE & GROWTH FACTOR REVIEWS
Volume 12, Issue 1, Pages 41-51Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1359-6101(00)00022-8
Keywords
caveolin; caveolae; signal transduction; cancer; muscular dystrophy
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Funding
- NIGMS NIH HHS [T32-GM07288] Funding Source: Medline
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Caveolins are a family of proteins that coat the cytoplasmic face of caveolae, vesicular invaginations of the plasma membrane. These proteins are central to the organization of the proteins and lipids that reside in caveolae. Caveolins transport cholesterol to and from caveolae, and they regulate the activity of signaling proteins that reside in caveolae. Through studying the genes encoding the caveolae coat proteins, we have learned much about how they perform these multiple functions. (C) 2001 Elsevier Science Ltd. All rights reserved.
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