Journal
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Volume 13, Issue 3, Pages 291-294Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00042737-200103000-00014
Keywords
hepatocellular carcinoma; percutaneous radiofrequency ablation; rapid progression; transcatheter arterial chemoembolization
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We report one patient who showed rapid progression of hepatocellular carcinoma (HCC) after undergoing transcatheter arterial chemoembolization (TACE) and percutaneous radiofrequency ablation (PRFA) for a small HCC measuring 2.5 cm in diameter. Enhanced magnetic resonance imaging (MRI) following treatment showed complete tumour necrosis and did not reveal the presence of a tumour around the treated area. Furthermore, the serum alpha-fetoprotein (AFP) level decreased at the completion of therapy, However, the HCC advanced in a very short time. Numerous tumours around the treated area were observed on enhanced computed tomography (CT) 50 days after PRFA. It is strongly suspected that the tumour was disseminated through the portal system because of the presence pattern of tumours. We believe this to be the first case illustrating a hepatic cancer that progressed rapidly following TACE and PRFA. Eur J Gastroenterol Hepatol 13:291-294 (C) 2001 Lippincott Williams & Wilkins.
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