Journal
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Volume 1787, Issue 11, Pages 1383-1394Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbabio.2008.12.012
Keywords
Calcium; Mitochondria; Ion channel; Endoplasmic reticulum; Cell signaling
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Funding
- Swiss National Science Foundation [31-118393/1, 31-120186/1]
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The role of mitochondria in cell signaling is becoming increasingly apparent, to an extent that the signaling role of mitochondria appears to have stolen the spotlight from their primary function as energy producers. In this chapter, we will review the ionic basis of calcium handling by mitochondria and discuss the mechanisms that these organelles use to regulate the activity of plasma membrane calcium channels and transporters. (C) 2009 Elsevier B.V. All rights reserved.
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