Journal
FRONTIERS IN BIOSCIENCE-LANDMARK
Volume 6, Issue -, Pages D456-D504Publisher
BIOSCIENCE RESEARCH INST-BRI
DOI: 10.2741/Zannis
Keywords
lipoproteins; apoproteins; apoA-I; apoA-II; apoA-IV; apoB; apoCI; apoCII; apoCIII; apoE; basal transcription complex; transcription factors; HNF-4; hormone nuclear receptors (PPAR, RXR, RAR, T3R beta); SP1; SREBP-1; SREBP-2; USF; ATF-2; Jun; SMAD; promoters; enhancers; transcriptional activation; transcriptional synergism; tissue-specific transcription; transgenic mice; signaling pathways (NF kappa B, SAPK/JNK, MAPK)
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Funding
- NHLBI NIH HHS [HL33952] Funding Source: Medline
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This review provides experiments and putative mechanisms which underlie the transcription of the human apolipoprotein genes in vitro and in vivo. Summarized below are the key findings for individual genes and gene clusters.
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