Related references
Note: Only part of the references are listed.Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma
Chad R. Schultz et al.
BIOCHEMICAL JOURNAL (2018)
Eukaryotic translation initiation factor 5A2 promotes metabolic reprogramming in hepatocellular carcinoma cells
Ting-Ting Cao et al.
CARCINOGENESIS (2017)
eIF5A Functions Globally in Translation Elongation and Termination
Anthony P. Schuller et al.
MOLECULAR CELL (2017)
eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences
Vicent Pelechano et al.
NUCLEIC ACIDS RESEARCH (2017)
A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening
Myung Hee Park et al.
AMINO ACIDS (2017)
Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome
Christian Schmidt et al.
NUCLEIC ACIDS RESEARCH (2016)
Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer
Shima Nakanishi et al.
AMINO ACIDS (2016)
Eukaryotic translation initiation factor 5A (eIF5A) is essential for HIF-1α activation in hypoxia
Mohammad Tariq et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Identification of a Selective SIRT2 Inhibitor and Its Anti-breast Cancer Activity
Asad Ali Shah et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2016)
Repositioning the Old Fungicide Ciclopirox for New Medical Uses
Tao Shen et al.
CURRENT PHARMACEUTICAL DESIGN (2016)
The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma
T. Muramatsu et al.
ONCOGENE (2016)
Prognostic significance of the expression of nuclear eukaryotic translation initiation factor 5A2 in human melanoma
Shahram Khosravi et al.
ONCOLOGY LETTERS (2016)
Mincle-mediated translational regulation is required for strong nitric oxide production and inflammation resolution
Wook-Bin Lee et al.
NATURE COMMUNICATIONS (2016)
Global quantitative proteomics reveal up-regulation of endoplasmic reticulum stress response proteins upon depletion of eIF5A in HeLa cells
Ajeet Mandal et al.
SCIENTIFIC REPORTS (2016)
Evidence for a Negative Cooperativity between eIF5A and eEF2 on Binding to the Ribosome
Danuza Rossi et al.
PLOS ONE (2016)
Enantiomers of 3-Methylspermidine Selectively Modulate Deoxyhypusine Synthesis and Reveal Important Determinants for Spermidine Transport
Mervi T. Hyvonen et al.
ACS CHEMICAL BIOLOGY (2015)
The translation factor eIF5A and human cancer
Michael B. Mathews et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2015)
Deoxyhypusine Modification of Eukaryotic Translation Initiation Factor 5A (eIF5A) Is Essential for Trypanosoma brucei Growth and for Expression of Polyprolyl-containing Proteins
Suong Nguyen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels
Ken Fujimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Biological Relevance and Therapeutic Potential of the Hypusine Modification System
Nora Paellmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Crystal Structure of the Peroxo-diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination
Zhenggang Han et al.
STRUCTURE (2015)
Overexpression of Eukaryotic Translation Initiation Factor 5A2 (EIF5A2) Correlates with Cell Aggressiveness and Poor Survival in Gastric Cancer
Qing-Bin Meng et al.
PLOS ONE (2015)
eIF5A has a function in the cotranslational translocation of proteins into the ER
Danuza Rossi et al.
AMINO ACIDS (2014)
Protective effects of polyamine depletion in mouse models of type 1 diabetes: implications for therapy
Sarah A. Tersey et al.
AMINO ACIDS (2014)
Blocking eIF5A Modification in Cervical Cancer Cells Alters the Expression of Cancer-Related Genes and Suppresses Cell Proliferation
Elisabeth Memin et al.
CANCER RESEARCH (2014)
The hypusine-containing translation factor eIF5A
Thomas E. Dever et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2014)
Hypusine Modification of the Ribosome-binding Protein eIF5A, a Target for New Anti-Inflammatory Drugs: Understanding the Action of the Inhibitor GC7 on a Murine Macrophage Cell Line
Oedem Jr et al.
CURRENT PHARMACEUTICAL DESIGN (2014)
A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation
Henning Sievert et al.
DISEASE MODELS & MECHANISMS (2014)
Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells
Nils A. Kulak et al.
NATURE METHODS (2014)
Genome-Wide Analyses and Functional Classification of Proline Repeat-Rich Proteins: Potential Role of eIF5A in Eukaryotic Evolution
Ajeet Mandal et al.
PLOS ONE (2014)
Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase
Avery G. Frey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients
Andrea Bandino et al.
CELLULAR ONCOLOGY (2014)
eIF5A isoforms and cancer: two brothers for two functions?
M. Caraglia et al.
AMINO ACIDS (2013)
Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5′-phosphatase interaction with c-Abl
D. Mokhtari et al.
DIABETOLOGIA (2013)
Deoxyhypusine Synthase Promotes Differentiation and Proliferation of T Helper Type 1 (Th1) Cells in Autoimmune Diabetes
Stephanie C. Colvin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
elF5A Promotes Translation of Polyproline Motifs
Erik Gutierrez et al.
MOLECULAR CELL (2013)
Translational Control of Inducible Nitric Oxide Synthase by p38 MAPK in Islet β-Cells
Yurika Nishiki et al.
MOLECULAR ENDOCRINOLOGY (2013)
EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues
Lili K. Doerfel et al.
SCIENCE (2013)
eIF5A interacts functionally with eEF2
Camila A. O. Dias et al.
AMINO ACIDS (2012)
Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development
Kazuhiro Nishimura et al.
AMINO ACIDS (2012)
Translational control of eIF5A in various diseases
Annette Kaiser
AMINO ACIDS (2012)
The Role of Acetylation in the Subcellular Localization of an Oncogenic Isoform of Translation Factor eIF5A
Muhammad Ishfaq et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2012)
Acetylation regulates subcellular localization of eukaryotic translation initiation factor 5A (eIF5A)
Muhammad Ishfaq et al.
FEBS LETTERS (2012)
Evaluation of deoxyhypusine synthase inhibitors targeting BCR-ABL positive leukemias
Patrick Ziegler et al.
INVESTIGATIONAL NEW DRUGS (2012)
Post-translational Modification by β-Lysylation Is Required for Activity of Escherichia coli Elongation Factor P (EF-P)
Jong-Hwan Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling
Andrew T. Templin et al.
CELL CYCLE (2011)
Unique modifications of translation elongation factors
Eva Greganova et al.
FEBS JOURNAL (2011)
Phosphorylation of maize eukaryotic translation initiation factor on Ser2 by catalytic subunit CK2
Elzbieta Lewandowska-Gnatowska et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2011)
Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae
Allen Henderson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Inhibition of Deoxyhypusine Synthase Enhances Islet β Cell Function and Survival in the Setting of Endoplasmic Reticulum Stress and Type 2 Diabetes
Reiesha D. Robbins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Revisiting an old acquaintance: role for elF5A in diabetes
Joachim Hauber
JOURNAL OF CLINICAL INVESTIGATION (2010)
The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice
Bernhard Maier et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Thermal Killing of Human Colon Cancer Cells Is Associated With the Loss of Eukaryotic Initiation Factor 5A
Alexander Gosslau et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
Slow peptide bond formation by proline and other N-alkylamino acids in translation
Michael Y. Pavlov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A
Mainul Hoque et al.
RETROVIROLOGY (2009)
Modulation of the Rate of Peptidyl Transfer on the Ribosome by the Nature of Substrates
Ingo Wohlgemuth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells
PMJ Clement et al.
FEBS JOURNAL (2006)
Reversal of the deoxyhypusine synthesis reaction - Generation of spermidine or homospermidine from deoxyhypusine by deoxyhypusine synthase
JH Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The eukaryotic initiation factor 5A is involved in the regulation of proliferation and apoptosis induced by interferon-α and EGF in human cancer cells
M Caraglia et al.
JOURNAL OF BIOCHEMISTRY (2003)
15-deoxyspergualin inhibits Akt kinase activation and phosphatidylcholine synthesis
M Kawada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitro
PMJ Clement et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Human EIF5A2 an chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression
ZA Jenkins et al.
GENOMICS (2001)
Share Paper
