Journal
BIOCHEMISTRY-MOSCOW
Volume 78, Issue 3, Pages 221-230Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0006297913030024
Keywords
miRNAs; siRNAs; piRNAs; biogenesis; regulation; functions
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Funding
- Doctoral Science Foundation of He Nan University of Science
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Recently, using large-scale genomic sequencing, a great number of small noncoding RNAs (ncRNA) has been discovered. Short ncRNAs can be classified into three major classes - small interfering RNA (siRNA), microRNA (miRNA), and piwi-interacting RNA (piRNA). These short ncRNAs ranging from 20 to 300 nt in size are now recognized as a new paradigm of gene regulation for controlling many biological processes. In this paper, we review the biogenesis and recent research on the functions of small regulatory non-coding RNAs and aim at understanding their important functions in living organisms. DOI: 10.1134/S0006297913030024
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