Journal
BIOCHEMISTRY-MOSCOW
Volume 76, Issue 7, Pages 862-866Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0006297911070170
Keywords
bacterial polysaccharides; natural antibodies; Burkholderia mallei; Burkholderia pseudomallei; Francisella tularensis
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Funding
- Presidium of the Russian Academy of Sciences
- European Commission
- German Federal Ministry of Education and Research
- Benzon Foundation
- Danish Research Council
- Danish Agency for Science, Technology and Innovation (FTP)
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The repertoire of natural anti-glycan antibodies in naive chickens and in chickens immunized with bacteria Burkholderia mallei, Burkholderia pseudomallei, and Francisella tularensis as well as with peptides from an outer membrane protein of B. pseudomallei was studied. A relatively restricted pattern of natural antibodies (first of all IgY against bacterial cell wall peptidoglycan fragments, L-Rha, and core N-acetyllactosamine) shrank and, moreover, the level of detectable antibodies decreased as a result of immunization.
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