Journal
BIOCHEMISTRY-MOSCOW
Volume 74, Issue 13, Pages 1505-1534Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0006297909130069
Keywords
spider venom; toxin; neurotoxin; cytolytic peptide; acylpolyamine; latrotoxin; toxic enzymes; protein structure and function; biosynthesis
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Funding
- Russian Foundation [08-04-00454, 08-04-90444]
- Federal Agency for Science and Innovation [NSh-639.2008.4]
- Federal Agency for Education [02.512.12.2020]
- Russian Federation [P1388]
- Russian Academy of Sciences
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Spider venom, a factor that has played a decisive role in the evolution of one of the most successful groups of living organisms, is reviewed. Unique molecular diversity of venom components including substances of variable structure (from simple low molecular weight compounds to large multidomain proteins) with different functions is considered. Special attention is given to the structure, properties, and biosynthesis of toxins of polypeptide nature.
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