Selenium dioxide E-methyl oxidation of suitably protected geranyl derivatives -: synthesis of farnesyl mimics

Difunctional allylic terpenes are important synthetic building blocks. Functionalisation of protected geranyl derivatives by SeO2 provides a convenient route to such compounds. The effect of the geranyl protecting group on the oxidation of the terminal E-methyl group was systematically investigated. (C) 2001 Elsevier Science Ltd. All rights reserved.