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Ganglioside GM3 and its biological functions

Journal

BIOCHEMISTRY-MOSCOW
Volume 74, Issue 3, Pages 235-249

Publisher

MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0006297909030018

Keywords

ganglioside GM3; GM3 synthase; metabolism; cell differentiation; proliferation; oncogenesis; apoptosis

Funding

  1. Russian Foundation for Basic Research [06-04-48277]

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Metabolism, topology, and possible mechanisms for regulation of the ganglioside GM3 content in the cell are reviewed. Under consideration are biological functions of GM3, such as involvement in cell differentiation, proliferation, oncogenesis, and apoptosis.

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