Journal
BIOCHEMISTRY-MOSCOW
Volume 73, Issue 4, Pages 393-405Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0006297908040032
Keywords
apoptosis; galectins; cell adhesion; lactosamine; carbohydrate specificity
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Galectins are a family of P-galactoside binding lectins, homological by a sequence of the carbobydrate-binding site. In this review literature data about structure and carbohydrate specificity of galectins are discussed. The role of galectins in the regulation of cell adhesion in immune response, inflammation, and cancer progression is considered.
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