Journal
INFECTION AND IMMUNITY
Volume 69, Issue 4, Pages 2723-2727Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.69.4.2723-2727.2001
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Funding
- NHLBI NIH HHS [HL59842, R01 HL059842] Funding Source: Medline
- NIAID NIH HHS [R37 AI033142, AI33142, AI33774, R01 AI033774, R01 AI033142, AI01341] Funding Source: Medline
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Rod like crystalline structures formed during eosinophilic Cryptococcus neoformans pneumonia in C57BL/6 mice. Crystals were found associated,vith yeast cells and free in host cell cytoplasm. The crystals apparently formed because of the interaction of a host protein with the cryptococcal polysaccharide. Crystal formation likely contributes to pathogenesis by causing cellular damage.
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