Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 5, Issue 2, Pages 112-119Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S1367-5931(00)00179-4
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There have been several recent advances in the area of biocatalysed hydrolytic kinetic resolution of epoxides using 'newly discovered' enzymes (i.e. epoxide hydrolases). These biocatalysts, two of which will become commercially available in the near future, appear to be highly promising tools for fine organic synthesis, as they enable the preparation of various epoxides and/or their corresponding diols in enantiopure form.
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