Journal
BIOCHEMISTRY
Volume 50, Issue 21, Pages 4399-4401Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bi200549x
Keywords
-
Categories
Funding
- Brookhaven National Laboratory/U.S. Department of Energy, Laboratory Directed Research and Development [08-022, 11-008]
- Office of Biological and Environmental Research, U.S. Department of Energy, the National Center for Research Resources [2 P41 RR012408]
- National Institute of General Medical Sciences [Y1 GM 0080-03, Y1-GM-1104]
- U.S. Department of Energy Office of Basic Energy Sciences [DE-AC02-98CH10886]
- National Cancer-Institute [Y1-CO-1020]
- U.S. Department of Energy, Basic Energy Sciences, Office of Science [DE-AC02-06CH11357]
Ask authors/readers for more resources
We demonstrate a general strategy for determining structures from showers of microcrystals. It uses acoustic droplet ejection to transfer 2.5 nL droplets from the surface of microcrystal slurries, through the air, onto mounting micromesh pins. Individual microcrystals are located by raster-scanning a several-micrometer X-ray beam across the cryocooled micromeshes. X-ray diffraction data sets merged from several micrometer-sized crystals are used to determine 1.8 angstrom resolution crystal structures.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
