Journal
JOURNAL OF MAGNETIC RESONANCE IMAGING
Volume 13, Issue 4, Pages 496-520Publisher
WILEY
DOI: 10.1002/jmri.1073
Keywords
cerebral blood volume; cerebral blood flow; mean transit time; transit time; magnetic resonance imaging; dynamic susceptibility contrast; contrast agent; bolus tracking; arterial spin labeling; arterial spin tagging; functional imaging; neuroimaging; review
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Numerous techniques have been proposed in the last 15 years to measure various perfusion-related parameters in the brain. In particular, two approaches have proven extremely successful: injection of paramagnetic contrast agents for measuring cerebral blood volumes (CBV) and arterial spin labeling (ASL) for measuring cerebral blood flows (CBF). This review presents the methodology of the different magnetic resonance imaging (MRI) techniques in use for CBV and CBF measurements and briefly discusses their limitations and potentials. (C) 2001 Wiley-Liss, Inc.
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