Journal
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
Volume 225, Issue 1-2, Pages 138-144Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0304-8853(00)01242-7
Keywords
biosensor; GMR; magnetoelectronics; DNA array; DNA hybridization; magnetic beads
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We describe a multi-analyte biosensor that uses magnetic microbeads as labels to detect DNA hybridization on a micro-fabricated chip. The beads are detected by giant magnetoresistance (GMR) magnetoelcctronic sensors embedded in the chip. The prototype device is a tabletop unit containing electronics, a chip carrier with a microfluidic flow cell, and a compact electromagnet and is capable of simultaneous detection of eight different analytes. (C) 2001 Elsevier Science B.V. All rights reserved.
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